Advanced Oncotherapy announces that Michael Sinclair, Executive Chairman of the Company, had yesterday purchased an option over 30 million ordinary shares of 1 penny each in the Company from Brahma AG at a cost of £300,000. The Option vests immediately, expires two years from today’s date and has an exercise price of 10p per Ordinary Share.

Following the above transaction, Michael Sinclair’s interest in the Company is as follows:

Ordinary Shares:                                                68,079,757

Options over Ordinary Shares:                           65,800,000

Warrants over Ordinary Shares:                         28,500,000

For further information contact:

Advanced Oncotherapy Plc	www.avoplc.com
Sanjeev Pandya, CEO	Tel: +44 20 3617 8728
Nicholas Serandour, CFO
Westhouse Securities (Nomad & Joint Broker)	Tel: +44 20 7601 6100
Antonio Bossi / David Coaten
Beaufort Securities (Joint Broker)	Tel: +44 20 7382 8300
Saif Janjua / Jon Levinson
Walbrook PR (Financial PR & IR)	Tel: +44 20 7933 8780 or avo@walbrookpr.com
Paul McManus / Anna Dunphy	Mob: +44 7980 541 893 / Mob: +44 7876 741 001