AVO1Advanced Oncotherapy plc (AVO), the developer of next-generation proton therapy systems for cancer treatment, will hold its Annual General Meeting at 12.00 noon at the Royal Institute of British Architects, 66 Portland Place, London W1B 1AD on Thursday, 30 June 2016.

The Company will provide shareholders with a short presentation on its development so far and its future plans.

A copy of the presentation, which does not contain any previously unpublished information that could be considered price sensitive, will be available from Thursday, 30 June 2016 on the Company’s website: www.avoplc.com

Advanced Oncotherapy Plc

www.avoplc.com

Michael Sinclair, Chief Executive Office

Tel: +44 20 3617 8728

Nicolas Serandour, Chief Operating and Financial Officer

Stockdale Securities (Nomad & Joint Broker)

Antonio Bossi / David Coaten

Tel: +44 20 7601 6100

Beaufort Securities (Joint Broker)

Jon Belliss / Elliot Hance

Tel: +44 20 7382 8300

Walbrook PR (Financial PR & IR)

Tel: +44 20 7933 8780 or avo@walbrookpr.com

Paul McManus / Anna Dunphy

Mob: +44 7980 541 893 / Mob: +44 7876 741 001